This is a Medical Research Council (MRC) priority area which aims to encourage integration of diverse experimental and observational approaches across various spatial and time scales, to advance our knowledge of human physiology and understanding of the emergence of disease.
This priority area aims to encourage the use of integrated methodologies allowing holistic approaches across the remits of all MRC Research Boards, with the goal of understanding how human health is maintained and disease emerges.
It is one of our MRC-wide priority areas that apply to all MRC boards and panels, which are used to help prioritise applications for funding.
Research proposals that meet this priority area will aim to expand our understanding of how disease emerges and include one or more of the following approaches:
- development and application of novel tools, technologies and methods to integrate multiple modalities and spatial and temporal biological, behavioural or social scales, spanning molecules, cells, tissues, organs, whole body, exposures or populations
- integration between complex multimodal data types, including genetic, cellular, polyomic, physiological, environmental, imaging, social or behavioural measurements
- integration of diverse experimental approaches to understand interactions between cell types, tissues and organs and identify mechanistic pathways, including those common to multiple conditions
Applications that fit this priority area will be assessed alongside other applications to the relevant boards.