The Medical Research Council (MRC) aims to support research of the highest scientific and ethical quality that will advance knowledge and its application to deliver benefits to the public.
We recognise, however, that there is a risk that the results of some types of research could potentially be misused to cause great harm. For example MRC funds basic and clinical research in infection and immunity, pathogens and host genetics which is essential to improve understanding of infectious diseases, and to enable scientists to improve diagnostics, vaccines, treatments and other control strategies, but which might be misused to develop biological weapons.
Our joint statement with the Biotechnology and Biological Sciences Research Council (BBSRC) and the Wellcome Trust on Managing Risks of Research Misuse (available as a document download under related content) updates and replaces the MRC position statement on bioterrorism and biomedical research published in 2005. The statement sets out a shared approach to managing these risks and describes how we think the broader research community should play their part in ensuring responsible conduct of research and innovation activities.
To contribute towards the UK’s efforts in addressing biosecurity concerns associated with the deliberate or accidental misuse of synthetic nucleic acids, whilst enabling and championing legitimate use, the Department for Science, Innovation and Technology (DSIT) has published guidance on screening synthetic nucleic acids for individuals and organisations involved in their provision, use, and transfer within the UK. The guidance sets baseline expectations, supports biosecurity measures, and aligns with the UK’s commitment to responsible innovation in engineering biology. Read the full guidance here: UK screening guidance on synthetic nucleic acids for users and providers – GOV.UK.
Last updated: 19 March 2025